Mayanka Awasthi

This study compares the virulence of MPXV clade IIa and IIb isolates in multiple murine models, finding IIb is significantly less virulent with lower lethality.

This study compares the attenuation of TNX-801, a recombinant chimeric Horsepox virus, to VACV-based vaccines in cell lines and mice, showing TNX-801 is significantly more attenuated.

This study evaluates the immunogenicity and efficacy of TNX-1800, a poxvirus vaccine expressing SARS-CoV-2 spike protein, in nonhuman primates challenged with SARS-CoV-2.

This study evaluates the immunogenicity and tolerability of the SARS-CoV-2 vaccine TNX-1800 in hamsters and rabbits, finding it well-tolerated with undetectable viral load after 28 days.