BiochemistryeLifePeer-reviewed
Early Steps of Protein Disaggregation by Hsp70 Chaperone and Class B J-Domain Proteins are Shaped by Hsp110
Wiktoria Sztangierska, Hubert Wyszkowski, Maria Pokornowska…·Agnieszka A. Klosowska
This study shows Hsp110 NEF enhances Hsp70 disaggregation of protein aggregates, particularly with Class B JDPs, and disrupts JDP-Hsp70 interactions to modulate disaggregation efficiency.
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