Cell BiologyeLifePeer-reviewed
Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain
Eva M. García‐Cuesta, Pablo Martínez, Karthik Selvaraju…·Mario Mellado
This paper identifies a small molecule that modulates CXCR4 nanoclustering without affecting ligand binding, improving therapeutic potential over existing CXCR4 antagonists.
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