Alisha N Jones

The paper identifies conserved RNA structural elements in UMLILO that mediate its interaction with WDR5, revealing a multivalent binding mechanism and functional role in gene regulation.

The paper characterizes the biophysical interactions between XIST E-Repeats and RNA-binding proteins, revealing cooperative binding and phase separation behavior that informs XIST's chromatin-modulating function.

This study reveals the structural and biophysical mechanisms of YicC, a novel bacterial RNase, showing its RNA binding and cleavage mechanism involving Mg2+ ions and dimeric conformations.

The paper investigates the multi-layered repression system controlling C9ORF72 translation and identifies strategies to rescue loss-of-function in disease.

This paper shows that RNA chemical probing reagents can react with protein amino acids, altering protein-RNA binding interactions.

This study shows that chemical probe concentration and size affect RNA structure and reactivity, leading to different 2D structure predictions.

This study identifies multiple structural conformations of lncRNAs using computational methods applied to SHAPE- and DMS-MaP datasets.

This study reveals how hnRNP A1 binds to the terminal loop of pri-mir-18a, destabilizing stem base-pairing to enhance miRNA processing.