Author

Darryl C. Zeldin

National Institute of Environmental Health SciencesORCID 0000-0002-2087-7307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

Abigail G. Kelly· 1 shared Anamitra GhoshiD· 1 shared Angeliki AsimakiiD· 1 shared Baijayanti Ghosh· 1 shared Bruce D. HammockiD· 1 shared Carlos Bueno‐BetíiD· 1 shared Chetan Singh RajpurohitiD· 1 shared Chuangye Qi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Abigail G. Kelly

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 20, 2026

Astrocytic sEH-EET signaling regulates microglial lysosomal function and suppresses the STING-Type I interferon pathway in Alzheimer's disease

Baijayanti Ghosh, Shuo Wang, Chuangye Qi…·Hui Zheng

This study identifies an astrocyte-microglia signaling axis in Alzheimer's disease where astrocytic sEH limits EET availability, promoting lysosomal clearance of pSTING and suppressing type I IFN signaling.

DOI 10.64898/2026.10.16.759679

mousescRNA-seq

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Cell BiologyJACC Basic to Translational SciencePeer-reviewedFeb 5, 2025

Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy

Dipak Panigrahy, Abigail G. Kelly, Katherine M. Quinlivan…·Jeffrey E. Saffitz

This study shows that inhibiting soluble epoxide hydrolase reduces inflammation and myocardial injury in arrhythmogenic cardiomyopathy by increasing pro-resolving lipid mediators.

8 citations

mouserat

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