Steven Kenneth Huang

This study identifies HuR as a regulator of GATA3-driven type 2 inflammation in asthma, showing its inhibition reduces lung inflammation and Th2 cytokine production.

This study shows WT1 promotes fibroblast survival and ECM production in IPF by impairing apoptotic clearance.

The paper identifies SorlA as a novel PAI-1 interactor required for lung fibrosis, showing SorlA deficiency protects against fibrosis in mice and SorlA is upregulated in human IPF lung tissue.

This study identifies CD103+ dendritic cell-fibroblast crosstalk via TLR9 and AHR signaling as a driver of lung fibrosis in IPF, showing that inhibiting AHR signaling reduces fibrosis.

DENetwork identifies regulatory and signaling networks behind differentially-expressed genes by integrating DE and non-DE genes in a graphical model, enhancing traditional differential gene analysis.

The paper uses single-cell RNA-seq to identify early ALS signatures in iPSC-derived motor neurons across multiple models and platforms.