Yuankai Huo

THiRST reconstructs 3D spatial transcriptomic data from serial 2D sections, improving cross-section consistency and enabling 3D gene expression analysis.

This study identifies genetic loci and pathways associated with limbic white matter microstructure in aging and Alzheimer's Disease using multi-cohort diffusion MRI and bulk RNA-seq data.

TRaP provides an open-source framework for reproducible Raman spectral preprocessing across different systems, enabling consistent and transparent analysis workflows.

scCotag improves single-cell multi-omics integration by using co-optimal transport and regularized barycentric mapping, outperforming existing methods in alignment and embedding accuracy.

This paper surveys computer vision methods for spatial transcriptomics, categorizing models and discussing challenges and future directions.

The paper identifies a novel epithelial cell type, LND, in Crohn's disease that is associated with immune dysregulation and disease activity.

The paper examines how sex, race, and APOE-ε4 allele status affect white matter microstructure across multiple aging and Alzheimer's disease cohorts.

This study quantifies superficial white matter volume and thickness across the lifespan using large datasets, finding unique age-related changes and relationships with cortical features.

The paper evaluates tractography reproducibility using empirical data from a single healthy volunteer scanned on two scanners, finding high consistency among top algorithms but variability due to tract volume containment.