Author

Carla Canal

Universitat Autònoma de BarcelonaORCID 0000-0002-2150-4836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Elisenda SanziD· 2 shared Paula SanchísiD· 2 shared Albert QuintanaiD· 1 shared Alessandro PrigioneiD· 1 shared Alex Gella· 1 shared Antonio del SoliD· 1 shared Berta Armengol· 1 shared Celia Munoz· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Elisenda SanzORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 12, 2026

PKR drives neuropathology in a mouse model of Leigh syndrome

Melania Gonzalez-Torres, Patrizia Bianchi, Marcos Blanco-Ramos…·Albert Quintana

The paper identifies PKR as a critical mediator of mitochondrial neuropathology in a mouse model of Leigh syndrome, showing its role in neuroinflammation and disease progression.

DOI 10.64898/2026.11.10.765677

mouseATAC-seq

𝕏 PostBluesky

NeuroscienceAlzheimer s Research & TherapyPeer-reviewedJun 9, 2026

Chronic central-targeted Interleukin-6 overexpression promotes hippocampal and cortical neuropathology in the Tg2576 mouse model of Alzheimer's disease

Carla Canal, Kevin Aguilar, Gemma Comes…·Juan Hidalgo

This study shows that chronic central IL-6 overexpression in Tg2576 mice worsens amyloidosis-related neuropathology and alters cortical and hippocampal gene expression, with sex-dependent effects.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 12, 2026

Regular parental exercise before mating influences offspring lower adiposity associated to hypothalamic neurodevelopmental changes

Celia Munoz, Carla Canal, Joel Vizueta, Paula Sanchís

This study shows that parental exercise before mating reduces offspring adiposity and affects hypothalamic gene expression in mice.

DOI 10.64898/2026.01.10.698777

mouseexperimental assay

𝕏 PostBluesky