Aly O. Abdelkareem

XenoSignal assesses ligand-receptor interactions across species using AlphaFold3 predictions to improve understanding of tumor-microenvironment crosstalk in xenograft models.

spOT-NMF improves spatial transcriptomics deconvolution by using optimal transport, outperforming existing methods in accuracy and scalability across various resolutions and species.

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.

This paper applies natural language processing techniques to identify viral sequences in metagenomes, comparing machine learning models with existing tools on simulated and real data.