Bo Young Ahn

This study shows that eIF5B is crucial for OSCC cell survival by enabling non-canonical translation of pro-survival mRNAs, and its inhibition reduces tumor growth and sensitizes cells to apoptosis.

The paper investigates sex differences in parvalbumin interneurons in healthy mice, finding females have fewer but more active and plastic inhibitory neurons in the retrosplenial cortex.

The paper identifies sex-dependent impairments in parvalbumin interneurons in the retrosplenial cortex as a cause of cognitive deficits in Alzheimer's disease and suggests targeting these neurons as a therapeutic strategy.

The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.