Author

Melanie Wurm

Boehringer Ingelheim (Austria)ORCID 0000-0002-2317-6952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1

Frequent Co-Authors

Aileen B. FrostiD· 1 shared Alessio CiulliiD· 1 shared Alexandra Hörmann· 1 shared Alexandra PopaiD· 1 shared Andre J. WijayaiD· 1 shared Andreas GollneriD· 1 shared Anna KöferleiD· 1 shared Arnel A. LauberiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aileen B. FrostORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologySciencePeer-reviewedSep 19, 2024

Targeting cancer with small molecule pan-KRAS degraders

Johannes Popow, William Farnaby, Andreas Gollner…·Alessio Ciulli

A single small molecule degrader targets 13 out of 17 prevalent oncogenic KRAS alleles, inhibiting growth of KRAS-driven cancer cell lines and inducing tumour regression in vivo.

219 citationstop 1%

humanexperimental assay

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GeneticseLifePeer-reviewedAug 8, 2023

Precision RNAi using synthetic shRNAmir target sites

Thomas Hoffmann, Alexandra Hörmann, Maja Corcokovic…·Ralph A. Neumüller

This paper introduces ARTi, a method using synthetic shRNAs to achieve precise and controllable RNAi for gene suppression.

3 citations

experimental assay

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