Author

Andre J. Wijaya

University of DundeeORCID 0009-0006-0378-376XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alessio CiulliiD· 2 shared David ZollmaniD· 2 shared William FarnabyiD· 2 shared Aileen B. FrostiD· 1 shared Alena KroupovaiD· 1 shared Andreas GollneriD· 1 shared Arnel A. LauberiD· 1 shared Barbara Kratochvil· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Alessio CiulliORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 15, 2024

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

Alena Kroupova, Valentina A. Spiteri, Zoe J. Rutter…·Alessio Ciulli

The paper introduces CRBNmidi, a Cereblon construct that enables high-resolution structural and biophysical studies of degraders without requiring DDB1 co-expression.

53 citationstop 2%

protein structureexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologySciencePeer-reviewedSep 19, 2024

Targeting cancer with small molecule pan-KRAS degraders

Johannes Popow, William Farnaby, Andreas Gollner…·Alessio Ciulli

A single small molecule degrader targets 13 out of 17 prevalent oncogenic KRAS alleles, inhibiting growth of KRAS-driven cancer cell lines and inducing tumour regression in vivo.

219 citationstop 1%

humanexperimental assay

𝕏 PostBluesky