Tarja A. Sironen

This study designs and validates protease-resistant antiviral peptides that inhibit SARS-CoV-2 fusion, showing improved efficacy in vitro and in vivo.

This study detects and characterizes coronaviruses in rodents and bats from four European countries, identifying new viral lineages and highlighting potential zoonotic risks.

The paper investigates TBEV circulation and vertical transmission in bank voles in Poland, finding co-circulating viral lineages and evidence of vertical transmission.

The paper investigates how biodiversity and habitat changes affect pathogen communities in European forests and urban areas, finding that host diversity increases pathogen richness but urbanization reduces certain pathogens.

The paper develops a yeast surface display library of bat antibodies to study humoral immunity to H9 influenza hemagglutinin, revealing structural and functional characteristics of bat antibodies.

The paper identifies Bartonella and hemotropic Mycoplasma species in synanthropic bats in Kenya and assesses their potential to infect humans.

This study identifies zoonotic viruses in Kenyan rodents and shrews, including rat hepatitis E virus and novel paramyxoviruses, highlighting the need for genomic surveillance.

This study shows that PUUV infection reduces survival of bank voles, especially young ones, in a natural setting, contradicting the expectation that reservoir hosts are unaffected.

The paper surveys zoonotic pathogens in small mammals across a forest anthropization gradient, finding pathogen richness and community structure vary with host species, site, and urban adaptation traits.

The paper develops a SARS-CoV-2 vaccine in mink and evaluates its immune response and efficacy against Alpha and Omicron variants, showing reduced severity and virus presence in vaccinated animals.

This study uses sewage metagenomics to distinguish seasonal, human-derived, and environmental microbial communities, offering potential for improved AMR surveillance.

The paper examines how ecological factors modify the relationship between spatial overlap and hantavirus infection likelihood in wild bank voles.

This paper introduces Lazypipe2, an improved metagenomic pipeline for virus detection, showing enhanced performance in identifying eukaryotic viruses and handling divergent sequences.

ClusTRace is a bioinformatic pipeline for analyzing clusters in SARS-CoV-2 phylogenies to detect super-spreading events and novel mutations.

The paper analyzes SARS-CoV-2 genomic data from Iraq during 2020-2021, identifying a high prevalence of the B.1.1.7 lineage with a stop codon mutation in ORF7a.

HaVoC is a bioinformatic pipeline that assembles SARS-CoV-2 sequences and identifies lineages to detect variants of concern.

The paper introduces a novel NGS pipeline called LAZYPIPE for virus discovery across diverse hosts and samples, demonstrating its ability to identify both known and novel viruses.