BioengineeringbioRxivPreprint
Preventing large deletions and chromosome loss in engineered human primary T cells by CasPlus with optimized guide RNAs
1 citation
Author
Qiaoyan Yang
NYU Langone HealthORCID 0000-0002-2353-6399Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2025 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewed
Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing
Colin T. Konishi, Nancy Mulaiese, Tanvi Butola…·Chengzu Long
This study corrects a pathogenic SERPINI1 mutation in iPSC-derived neurons using a personalized base editor to treat FENIB and related neurodegenerative diseases.
6 citations - GeneticsbioRxivPreprint
Mutating PINK1 gene by paired truncated sgRNA/Cas9-D10A in Cynomolgus Monkey
Zhenzhen Chen, Jian‐Ying Wang, Yu Kang…·Yuyu Niu
The paper describes the generation of PINK1 mutant cynomolgus monkeys using paired truncated sgRNA/Cas9-D10A to create a primate model of Parkinson's disease without affecting PINK1 protein expression.