Brian Robert Walker

This study investigates corticosterone metabolism and dynamics in humans, finding it has faster turnover, greater metabolism, and a stronger ACTH response compared to cortisol.

This study identifies CBR1 as a regulator of blood pressure in Down Syndrome, showing that its inhibition can increase blood pressure in a DS mouse model.

This study shows that ABCC1 deficiency in male mice affects glucose metabolism and insulin tolerance on a high-fat diet without altering tissue corticosterone levels.

The paper identifies genetic variants associated with plasma cortisol and cardiovascular disease, revealing gene networks in liver and adipose tissues regulated by corticosteroid binding globulin and the glucocorticoid receptor.

This study identifies Cystatin C as a glucocorticoid-responsive factor that recruits Trem2+ macrophages and predicts immunotherapy failure in cancer.

This study examines heritability of urinary metabolites in children, finding substantial genetic contributions across amines, organic acids, and steroids.

The paper investigates genetic correlations between psychiatric and immune-related phenotypes using GWAS summary data, finding significant shared genetic variants.