Cell BiologyScience AdvancesPeer-reviewed
Repression of mRNA translation initiation by GIGYF1 via blocking the eIF3-eIF4G1 interaction
Jung‐Hyun Choi, Jun Luo, Geoffrey G. Hesketh…·Seyed Mehdi Jafarnejad
This study identifies GIGYF1 as a repressor of mRNA translation by disrupting the eIF3-eIF4G1 interaction, enhancing host immune response by derepressing Ifnb1 mRNA.
10 citations