Author
Lunenfeld-Tanenbaum Research InstituteORCID 0000-0002-5570-7615Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Kam Shan Hu, Anne Norris, Wilmer R. Rodriguez-Polanco…·Barth D. Grant
This study identifies SCM-1/SCAMP as a key factor maintaining microdomain boundaries in the endosomal system, ensuring proper cargo sorting and preventing microdomain overlap.
Laura A. Orofiamma, Ralph Christian Delos Santos, Ayshin Mehrabi…·Costin N. Antonescu
This study shows AMPK regulates clathrin-mediated endocytosis by controlling Dab2 and Arf6 to selectively internalize β1-integrin.
Diana Schwendener Forkel, Osemudiamen Ibazebo, Sumaiya A. Soha…·Costin N. Antonescu
The paper shows that GATOR1 regulates GSK3β nuclear localization in response to amino acids, independent of mTORC1, and that this process supports cell survival under metabolic stress.
Jung-Hyun Choi, Jun Luo, Geoffrey G. Hesketh…·Seyed Mehdi Jafarnejad
This study identifies GIGYF1 as a repressor of mRNA translation by disrupting the eIF3-eIF4G1 interaction, enhancing host immune response by derepressing Ifnb1 mRNA.
Christopher D. Go, James D.R. Knight, Archita Rajasekharan…·Anne‐Claude Gingras
Profiling 192 subcellular markers by proximity-dependent biotinylation (BioID) in human HEK 293 cells maps 4,145 proteins across 32 compartments via 35,902 interactions, available with analysis tools at humancellmap.org.