Author

Jung‐Hyun Choi

Institut du cancer Rosalind & Morris GoodmanORCID 0000-0002-8992-4992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Angelos Pistofidis· 2 shared Nahum SonenbergiD· 2 shared Reese Jalal Ladak· 2 shared Seyed Mehdi JafarnejadiD· 2 shared T. Martin SchmeingiD· 2 shared Andrei V. BakiniD· 1 shared Anne‐Claude GingrasiD· 1 shared Atina G. CotéiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Angelos Pistofidis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Systems BiologybioRxivPreprintSep 2, 2025

A Proteome-Wide Gain-of-Function Atlas Mapping the Landscape of Chemotherapy Response

Kyeong Beom Jo, Mohammed Alruwaili, Da-Eun Kim…·Dae‐Kyum Kim

This study creates a proteome-wide gain-of-function atlas to map chemotherapy responses and identifies drug combinations to overcome resistance.

2 citations

humanproteomics

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Molecular BiologybioRxivPreprintFeb 28, 2025

No evidence that human GIGYF2 interacts with growth factor receptor-bound protein 10 (GRB10): implication for human disease

Jung‐Hyun Choi, Israel Shpilman, Niaz Mahmood…·Nahum Sonenberg

The paper shows that human GIGYF2 does not interact with GRB10, challenging the current understanding of their role in disease.

DOI 10.1101/2025.02.28.640929

humanexperimental assay

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Cell BiologyScience AdvancesPeer-reviewedJul 17, 2024

Repression of mRNA translation initiation by GIGYF1 via blocking the eIF3-eIF4G1 interaction

Jung‐Hyun Choi, Jun Luo, Geoffrey G. Hesketh…·Seyed Mehdi Jafarnejad

This study identifies GIGYF1 as a repressor of mRNA translation by disrupting the eIF3-eIF4G1 interaction, enhancing host immune response by derepressing Ifnb1 mRNA.

10 citations

humanmetagenomics

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NeurosciencebioRxivPreprintDec 26, 2018

Transcriptional activation of DBP by hnRNP K facilitates circadian rhythm.

Paul Kwangho Kwon, Kyung‐Ha Lee, Ji-hyung Kim…·Kyong‐Tai Kim

This study identifies hnRNP K as a transcriptional amplifier of DBP, regulating circadian rhythms through chromatin accessibility and mRNA stabilization in Drosophila.

DOI 10.1101/503771

Drosophilaexperimental assay

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