Author

Yanchen Dong

Research Institute of the McGill University Health CentreORCID 0000-0002-2449-3634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:multiome· 1

Frequent Co-Authors

Loydie Anne Jerome‐MajewskaiD· 2 shared Sabrina Shameen AlamiD· 2 shared Eric BarekeiD· 1 shared Florian HeydiD· 1 shared Hesso FarhaniD· 1 shared Jacek MajewskiiD· 1 shared Jennelle SmithiD· 1 shared Marco PreußneriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Loydie Anne Jerome‐MajewskaORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 3, 2026

Developmental pleiotropy revealed by mosaic heterozygous Snrpb deletion underlies CCMS-like axial skeletal defects

Yanchen Dong, Eric Bareke, Marilou Paquin…·Loydie Anne Jerome‐Majewska

This study uses a mouse model to show that Snrpb deletion causes axial skeletal defects by disrupting p53 and RA signaling, without affecting somite patterning.

DOI 10.64898/2026.09.02.748635

mousebulk RNA-seq

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Cell BiologybioRxivPreprintSep 28, 2023

Identification of a link between splicing and endoplasmic reticulum proteostasis

Muhammad Zahoor, Yanchen Dong, Marco Preußner…·Hesso Farhan

This study identifies SNRPB as a regulator of ER export and links it to osteogenesis and CCMS through its effects on splicing and the UPR.

DOI 10.1101/2023.09.28.559974

mouseproteomics

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