Kacey N. Mersch

This study compares ssDNA translocation and helicase activities of covalent dimers and monomers of E. coli UvrD, showing higher processivity and DNA unwinding in dimers.

This study identifies a conserved dimerization mechanism in SF1A UvrD-family helicases, showing that the 2B domain mediates dimerization and activation across multiple species.

This study shows that the nuclease domain of E. coli RecBCD affects dsDNA unwinding rates but not ssDNA translocation, suggesting the nuclease domain influences base pair melting rather than translocation.