Ojas Singh

The paper integrates glycosylation filtering into a protein design pipeline to improve efficiency and reduce costs in binder design.

This study investigates Siglec-6's binding mechanism to gangliosides, showing it relies on both conserved and membrane-associated residues for effective recognition.

This paper identifies sequence determinants that regulate oligosaccharyltransferase (OST) catalytic efficiency and glycosylation specificity in proteins.

The paper introduces GlycoShape, an open-access database and tool to restore glycosylation to protein structures using molecular dynamics simulations and public structural data.

This study shows that bacterial ADP-heptose triggers a revival stem cell program in the intestinal epithelium by inducing Paneth cell dedifferentiation and ISC loss.