Lenka Dohnalová

The paper identifies lithocholic acid as a bile acid metabolite that modulates circadian rhythms in intestinal cells by affecting core clock proteins and feedback loops.

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

This study shows that diet can significantly affect survival in a mouse model of Hirschsprung disease by altering gut microbes, metabolites, and epithelial gene expression.