Author
Jie Chen
Harvard UniversityORCID 0000-0002-2852-3618Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links4 papers
Recent·Most cited
- Cancer BiologyNature CommunicationsPeer-reviewed8 citationstop 1%
- Cancer BiologybioRxivPreprint
Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis
Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird
This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.
3 citations - Cancer BiologybioRxivPreprint
Direct and abscopal anti-tumor responses elicited by peripheral nerve schwannoma irradiation synergize with anti-PD1 treatment in vestibular schwannoma models
Zhenzhen Yin, Simeng Lu, Limeng Wu…·Lei Xu
This study shows that combining anti-PD1 treatment with radiation therapy for vestibular schwannomas improves tumor control, reduces radiation dose, and elicits systemic anti-tumor effects.
DOI 10.1101/2024.12.29.630655 - ImmunologybioRxivPreprint
Targeting Interferon-Driven Inflammatory Memory Prevents Epigenetic Evolution of Cancer Immunotherapy Resistance
Jingya Qiu, Darwin Ye, Xinyi E. Chen…·Andy J. Minn
This study identifies inflammatory memory as a mechanism for cancer resistance to immunotherapy and shows that combining JAK and TBK1 inhibitors can prevent it.
5 citations