Takayuki Shimizu

This study introduces regioselective bacterial heme oxygenases into Arabidopsis hy1-1 to test the retrograde heme signaling hypothesis, showing differential complementation of phenotypes related to phytochrome assembly and heme signaling.

This study shows that RLF, a heme-binding protein, is essential for organ development in Marchantia polymorpha and is evolutionarily conserved with a role in Arabidopsis thaliana.

This study identifies GUN1's role in chloroplast-to-nucleus retrograde signaling by showing it binds heme, affects tetrapyrrole biosynthesis, and enhances FC1 activity.