Author
Jer-En Hsu
University of MichiganORCID 0000-0002-2968-1853Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links4 papers
Recent·Most cited
- PhysiologyFEBS JournalPeer-reviewed12 citations
- PathologyJCI InsightPeer-reviewed
Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy
Jer-En Hsu, Qingyang Zhao, Weiqiu Cheng…·Jun Hee Lee
This study combines histopathology and spatial transcriptomics to show that mTORC1 hyperactivation causes fiber-type-specific pathological changes in skeletal muscle.
DOI 10.1172/jci.insight.203167 - GenomicsNature CommunicationsPeer-reviewed
Seq-Scope-eXpanded: Spatial Omics Beyond Optical Resolution
Angelo Anacleto, Weiqiu Cheng, Qianlu Feng…·Jun Yong Lee
Seq-Scope-X improves spatial transcriptomics resolution by expanding tissues, revealing detailed nuclear and cytoplasmic transcriptome differences in liver cells and enabling proteomic analysis in other tissues.
- GenomicsNature ProtocolsPeer-reviewed
Seq-Scope Protocol: Repurposing Illumina Sequencing Flow Cells for High-Resolution Spatial Transcriptomics
Yongsung Kim, Weiqiu Cheng, Chun‐Seok Cho…·Jun Hee Lee
This paper describes a protocol to repurpose Illumina sequencing flow cells for high-resolution spatial transcriptomics, enabling detailed spatial gene expression analysis with improved resolution and cost efficiency.