PathologyJCI InsightPeer-reviewed
Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy
Jer-En Hsu, Qingyang Zhao, Weiqiu Cheng…·Jun Hee Lee
This study combines histopathology and spatial transcriptomics to show that mTORC1 hyperactivation causes fiber-type-specific pathological changes in skeletal muscle.
DOI 10.1172/jci.insight.203167