Purushottam Babu Tiwari

The paper identifies cisplatin as an RNA binder and shows its cytotoxicity is partially mediated through RNA binding, revealing a noncanonical mechanism of action.

This study shows chlorpromazine inhibits EAG1 channels by disrupting PAS-CNBH domain coupling, without affecting VSD movement.

This paper develops a yeast-based screening system to identify human TOP1 poison inhibitors and catalytic inhibitors, distinguishing their mechanisms and assessing cytotoxicity.