Author

Lee H. Chen

University of California, San FranciscoORCID 0000-0002-3176-0964Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aaron A. DiaziD· 2 shared Akane YamamichiiD· 2 shared Arun P. WiitaiD· 2 shared Chibo Hong· 2 shared Darwin W. KwokiD· 2 shared Hideho OkadaiD· 2 shared Joanna J. PhillipsiD· 2 shared Joseph F. CostelloiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Aaron A. DiazORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedFeb 19, 2025

Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens

Darwin W. Kwok, Nicholas O. Stevers, Iñaki Etxeberría…·Hideho Okada

The paper identifies tumor-wide splicing aberrations that generate public neoantigens, enabling T-cell-based immunotherapies targeting intratumoral heterogeneity.

112 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyScientific ReportsPeer-reviewedMar 16, 2024

Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma

Takahide Nejo, Lin Wang, Kevin Leung…·Hideho Okada

The paper identifies tumor-specific alternative splicing events in glioma that could generate cell-surface antigens but finds significant spatiotemporal heterogeneity and lack of proteomic evidence.

17 citations

humanbulk RNA-seq

𝕏 PostBluesky