Steven W. Millward

This study identifies DIRAS3 as a tumor suppressor that inhibits diverse oncogenic KRAS variants through a specific inhibitory interface, with a mimetic showing broad suppression of KRAS-driven signaling.

This study develops hyperpolarized silicon particles functionalized with MUC1 antibody for targeted molecular MRI of colorectal cancer, showing active tumor targeting in vivo.

This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.