Zheng‐Jiang Zhu

This study identifies ZBTB17/MIZ1 as a peroxisome regulator through CRISPR screens, showing its role in protein import and metabolic regulation.

This paper introduces KGMN, a method for annotating unknown metabolites in untargeted metabolomics by integrating multiple networks, and validates several unknowns through computational and experimental approaches.

metID automates compound annotation for LC-MS data by integrating multiple databases, improving efficiency and reproducibility.

MS-DIAL 4 provides a comprehensive lipidome atlas with retention time, collision cross section, and MS/MS data to standardize and accelerate lipidomics research.

The paper introduces a recursive algorithm and webserver, MetDNA, for large-scale and unambiguous metabolite identification in untargeted metabolomics.

This study shows that aging causes H3K27me3 drift, reducing glycolytic gene expression and lifespan, while PRCs-deficiency or glycolytic gene increase improves longevity.