Author

Julio Furlong-Silva

University of ExeterORCID 0000-0002-3313-8650Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew S. MacDonaldiD· 3 shared Daniel P. ConniD· 3 shared Peter C. CookiD· 3 shared Emma L. HoulderiD· 2 shared George VereiD· 2 shared Stefano A. P. ColomboiD· 2 shared Ana Cruz· 1 shared Bethany L. McCanniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

Andrew S. MacDonaldORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 13, 2025

Mgl2+ cDC2 triggering of fungal allergic inflammation depends on a spore induced glycolytic shift fuelled by local availability of glucose

Julio Furlong-Silva, George Vere, Phuong Tuyen Nguyen…·Peter C. Cook

This study shows that Mgl2+ cDC2s trigger fungal allergic inflammation through a glycolytic shift driven by glucose availability after spore uptake.

1 citation

mousebulk RNA-seq

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ImmunologyNature CommunicationsPeer-reviewedJan 22, 2025

Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation.

Peter C. Cook, Sheila L. Brown, Emma L. Houlder…·Andrew S. MacDonald

The paper identifies Mgl2+ cDC2s as key drivers of type 2, but not type 17, fungal allergic airway inflammation in mice.

24 citationstop 1%

mousebulk RNA-seq

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ImmunologyJournal of Allergy and Clinical ImmunologyPeer-reviewedNov 22, 2024

Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype, a process that can be targeted via antifungal therapeutics.

Emma L. Houlder, Sara Gago, George Vere…·Peter C. Cook

This study identifies a specific stage of Aspergillus fumigatus spore development that activates dendritic cells to trigger allergic airway inflammation and shows antifungal drugs can reduce this process.

9 citations

mouseexperimental assay

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