Author
Baylor College of MedicineORCID 0000-0002-3323-2815Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Faith M Joseph, Matthew V. Holt, John Michael Jerome…·Nicolas L. Young
This paper identifies KDM4A-mediated H2AX truncation as a mechanism that suppresses DNA damage response signaling by preventing γH2AX formation.
Karl F. Poncha, Alyssa T. Paparella, Nicolas L. Young
The paper introduces two new PTM crosstalk scores to analyze histone proteoform dynamics in mouse organs during aging and demonstrates their application using proteoform data.
Geoffrey Fox, Karl F. Poncha, B Rutledge Smith…·Kanishk Jain
The paper shows that H3K18 and H3K23 acetylation enhance MLL1-mediated H3K4 methylation, while other modifications are less affected by tail acetylation.
Bethany C. Taylor, Loic H. Steinthal, Michelle Dias…·Alli M. Nuotio-Antar
The paper quantifies histone modifications and DNA methylation in mouse BAT under different cold conditions, revealing epigenetic changes linked to thermogenic response.
Yan Xiong, Jaiprakash Sharma, Meggie N. Young…·Marco Sardiello
This study identifies an IKK/β-TrCP2 phosphorylation-ubiquitination cascade that regulates TFEB stability, independent of other regulators.