Tomos E. Morgan

The paper identifies a conserved interaction between Bim1 and the Ndc80 complex in S. cerevisiae, showing it enhances microtubule attachment strength and is regulated by phosphorylation.

This study identifies a conserved interaction between Bim1 and the Ndc80 complex in S. cerevisiae, showing it enhances microtubule attachment strength and is regulated by phosphorylation.

The paper identifies a positive feedback loop between GABARAP and PtdIns3K-C1 that drives PtdIns3P production, essential for autophagosome biogenesis.

This paper expands the genetic code by incorporating non-canonical monomers into proteins using evolved tRNAs and orthogonal synthetases, enabling broader sequence context compatibility.

This study uses cryo-EM to reveal structural mechanisms of KMN complex assembly and phospho-regulation in budding yeast kinetochores.

The paper shows phosphorylation modulates deadenylation rates via multivalent interactions in RNA adaptors, enabling graded regulation of mRNA decay.

This study identifies the structural basis of RECQL5-induced RNA polymerase II transcription braking and reveals its coordination with the TCR complex for reactivation.

This study identifies how Orientia tsutsugamushi uses ScaC to recruit BICD2 for dynein-based motility, revealing a mechanism for bacterial transport within host cells.

This study determines the cryo-EM structure of the MmpS5L5 efflux pump in Mycobacterium tuberculosis and identifies mutations that enhance bedaquiline efflux, suggesting new resistance mechanisms.

The paper shows KIF1C activates and enhances dynein movement via the FHF cargo adaptor, revealing a mechanism for motor co-dependency.