Thomas D. Nightingale

This paper shows that Piezo1 mechanosensing triggers endothelial Weibel-Palade body exocytosis, linking mechanical forces to inflammation and haemostasis through VWF release and leukocyte capture.

This study identifies β-PIX as a regulator of VWF secretion from endothelial cells by enabling cytoskeletal reorganisation during WPB exocytosis.

This study identifies Myosin-1C's role in enhancing endothelial secretion of von Willebrand factor by linking actomyosin machinery to the plasma membrane during exocytosis.