GenomicsGenome ResearchPeer-reviewed
Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise
Aliza B. Rubenstein, Gregory R. Smith, Zidong Zhang…·Stuart C. Sealfon
The paper uses single-nucleus multiome sequencing to analyze gene regulatory changes in human skeletal muscle after endurance exercise, identifying fiber-type specific regulatory programs and transcription factor networks.