Author
Broad InstituteORCID 0000-0002-3453-7514Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Matteo Mazzocca, Domenic N. Narducci, Simon Grosse‐Holz…·Anders S. Hansen
The paper tracks chromatin dynamics across seven orders of magnitude in human and mouse cells, finding strongly subdiffusive behavior with limited sensitivity to transcription and histone modifications.
Catherine Do, Guimei Jiang, Giulia Cova…·Jane A. Skok
The paper investigates how CTCF mutations affect chromatin accessibility, cohesin binding, and gene regulation through multivariate modeling and mutant perturbations.
Domenic N. Narducci, Anders S. Hansen
The paper shows ZNF143/ZFP143 is an essential transcription factor with no general looping function, functioning independently of CTCF and regulating mitochondrial and ribosomal genes.
Gavin Schlissel, Miram Meziane, Domenic N. Narducci…·Pulin Li
The paper shows SCUBE1 expands Hedgehog gradients by enabling transient diffusion through cell gaps, revealing a topology-limited diffusion mechanism for morphogen signaling.