Cesare Granata

This study profiles bioenergetic changes in fresh human kidney tissue from diabetic patients with preserved function, revealing compensatory metabolic adaptation and intrinsic mitochondrial dysfunction.

This study shows reduced mitochondrial ketone body oxidation in insulin resistant states across multiple organs in humans and mice.

This study shows that blood glucose levels directly affect mitochondrial function and metabolism in early diabetic kidney disease, with changes in proteome, metabolome, and lipidome.

This study compares exercise-induced changes in autophagy markers in human and rodent skeletal muscle, finding differences in LC3B-II protein levels and autophagy flux responses.