Daniel Lozano‐Ojalvo

This study shows that inhibiting Epac1 with AM-001 reduces fibroblast proliferation and profibrotic markers, protecting against pulmonary fibrosis in mouse models and human lung slices.

This study identifies an oncofetal cell state that contributes to resistance in colorectal cancer and shows that targeting both this state and LGR5+ CSCs is needed for effective treatment.

The paper identifies anti-correlated gene selection as a method to prevent false discovery of subpopulations in scRNA-seq by reducing erroneous subdivisions in clustering.