Fabrizio Pin

This study shows chemotherapy causes NAD+ loss in muscle and liver, with Nrk2 downregulation linked to muscle wasting across multiple models.

This study shows GL261 glioblastoma tumors in young mice reduce skeletal muscle growth, mass, and protein synthesis while altering catabolism signaling.

This study shows that irisin deletion affects murine osteocyte function differently in males and females, with protection in females under calcium deficiency and increased bone loss in males.

This study shows that PGC-1α in myofibers increases myogenic progenitors and reduces adipogenesis, enhancing muscle regeneration.