Maureen A. Su

This study shows that Xist-mediated gene silencing supports CD4+ T cell persistence and colitogenic capacity, contributing to autoimmunity.

This study shows that KMT2D promotes effector molecule release in NK cells by regulating H3K4me1 and RAB3D levels, affecting cytotoxicity and cytokine production.

This study identifies age-associated senescent CD4+ T cells as drivers of autoimmunity in CIDP, showing that senolytic and senomorphic therapies can mitigate disease.

This study shows that ablating cardiac TRPV1 afferents after completed myocardial infarction reduces arrhythmogenic remodeling and improves cardiac function.

This study shows HIV-1 infected immune cells alter cervical cancer pathways through paracrine signals, with upregulated PI3K-AKT and interferon-stimulated genes.

This study identifies UTX's role in regulating progenitor CD8+ T cell fate in T1D by interacting with TCF1 and STAT3, showing its importance in autoimmune diabetes progression.

This paper identifies polyfunctional IL-21+ IFNγ+ T follicular helper cells as drivers of ICI-induced diabetes and shows JAK inhibitors can prevent this autoimmune condition.

The paper identifies IL-21-expressing CD4+ T cells in an inflammatory neuropathy mouse model and shows their role in neuropathy development through clonal expansion and CXCR6-mediated infiltration.