Nicholas A. Pudlo

This study identifies the enzymatic pathway used by Bacteroides thetaiotaomicron to degrade colonic mucin O-glycans and shows that multiple exo-acting enzymes are critical for gut colonization.

The paper identifies and characterizes a functional LolB ortholog in Bacteroides that rescues E. coli's lethal phenotype and shows its role in lipoprotein transport.

This study shows that specific carbohydrates modulate phage resistance in Bacteroides thetaiotaomicron through phase variable S-layers and the pentose phosphate pathway.

This paper investigates how acarbose affects two Bacteroides species, showing that Bt growth is inhibited while Bo growth is not, revealing complex mechanisms involving Sus system interactions and differential gene expression.

This study shows that Akkermansia muciniphila increases susceptibility to a gut pathogen under fiber-deprived conditions but reduces pathogen load on a fiber-sufficient diet.

The paper identifies a ribose utilization system in Bacteroides thetaiotaomicron that is essential for gut colonization and shows its diet-dependent role through metabolic context.