Eric C. Martens

This study shows that intestinal Bacteroides species degrade tryptophan into indoles, which enhance anti-tumor immunity and limit melanoma growth.

This study identifies the enzymatic pathway used by Bacteroides thetaiotaomicron to degrade colonic mucin O-glycans and shows that multiple exo-acting enzymes are critical for gut colonization.

The paper identifies and characterizes a functional LolB ortholog in Bacteroides that rescues E. coli's lethal phenotype and shows its role in lipoprotein transport.

This study identifies the group B [FeFe]-hydrogenase as the primary enzyme driving fermentative H2 production in the human gut, linking it to gut health and disease.

This study shows that specific carbohydrates modulate phage resistance in Bacteroides thetaiotaomicron through phase variable S-layers and the pentose phosphate pathway.

This study investigates the role of Akkermansia muciniphila sulfatases in colonic mucin utilization, revealing unique adaptations compared to Bacteroides species.

This paper investigates how acarbose affects two Bacteroides species, showing that Bt growth is inhibited while Bo growth is not, revealing complex mechanisms involving Sus system interactions and differential gene expression.

This study identifies Ruminococcus torques as a keystone mucin-degrading bacterium that releases oligosaccharides accessible to Bacteroides thetaiotaomicron, linking its role to inflammatory bowel disease.

This study shows that Akkermansia muciniphila increases susceptibility to a gut pathogen under fiber-deprived conditions but reduces pathogen load on a fiber-sufficient diet.

This study shows that dietary fibre deprivation and bacterial curli exposure worsen PD-like symptoms in mice overexpressing human alpha-synuclein.

The paper identifies a ribose utilization system in Bacteroides thetaiotaomicron that is essential for gut colonization and shows its diet-dependent role through metabolic context.