Kim Ohl

This study develops an in vitro model to assess endothelial dysfunction under inflammatory stress and finds that combined LPS and PBMC exposure significantly impairs endothelial confluence and increases adhesion molecule expression.

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

The paper identifies mutations in the C2orf69 gene as the cause of a human multisystem disorder characterized by autoinflammation, leukoencephalopathy, and hepatopathy.