Bernd Jagla

CyFj11 enables importing FlowJo v11 workspaces into R and exporting R-based gates back to FlowJo, ensuring interoperability between gating tools and statistical analysis environments.

This study uses single-cell RNA-seq to show that NK cells reprogram transcriptionally and functionally after Streptococcus pneumoniae infection, revealing new roles in bacterial immunity.

The paper identifies the origin, fate, and clonal contribution of endocardial progenitors to the development of the cardiac mitral valve using single-cell RNA sequencing and genetic tracing in mice.

The paper shows that cardiac macrophages in pigs with right ventricular failure drive cardiomyocyte de-differentiation and regeneration through epimorphosis.

SCHNAPPs is a Shiny-based tool for bench-scientists to analyze scRNA-seq data, offering quality control, clustering, differential expression, and visualization with reproducible reporting.