Xiaona Huang

The paper identifies two novel proteins, EGC-2 and EGC-3, that are essential for E granule assembly and small RNA homeostasis in C. elegans using TurboID-based proximity labeling and RNAi screening.

This study shows that rRNA intermediates influence nucleolar structure in C. elegans by altering protein distribution and causing architectural changes.

The paper identifies subcompartments within C. elegans germ granules and maps perinuclear proteins to specific regions, revealing a novel D granule and the role of MIP-1/EDDG-1 in germ granule architecture.

The paper identifies a new subcompartment in C. elegans germ granules that facilitates specialized small RNA production, essential for fertility and RNAi response.