Elamaran Meibalan

This study shows that severe malarial anaemia is linked to increased red blood cell production, iron metabolism, tissue injury, and parasite biomass in bone marrow, with better resolution from bone marrow analysis than peripheral blood.

The paper performs a meta-analysis of scRNA-seq data to identify disease-specific and shared chemokine-based cell communication patterns in immune diseases.

The paper develops engineered microvascular networks with a KLF2 reporter to study flow effects on vascular structure and function, finding increased KLF2 expression correlates with larger vessel diameters and improved barrier function.

The paper uses single-nuclei RNA-seq and spatial transcriptomics to analyze gene expression changes in the right atrium of patients with ischemic heart disease, revealing inflammatory microvascular dysfunction and altered tissue composition.