Author

Yen‐Chung Lai

Scripps Research InstituteORCID 0000-0002-3844-3080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Dennis R. BurtoniD· 2 shared Justin Ndihokubwayo· 2 shared Nathan BeutleriD· 2 shared Thomas F. RogersiD· 2 shared Alessia LiguoriiD· 1 shared Andrew B. WardiD· 1 shared Bruno E. CorreiaiD· 1 shared Danny LuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Dennis R. BurtonORCID

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2 papers

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedApr 7, 2026

Deep learning-enabled scaffolding of spatial arrays of PfCSP epitopes

Nelson R. Wu, Karla M. Castro, Nathan Beutler…·William R. Schief

This study uses deep learning to design multi-epitope scaffolds mimicking CSP's spatial structure, showing accurate positioning of two epitopes and partial success with the third.

DOI 10.1073/pnas.2521914123

deep learningprotein structure prediction

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ImmunologybioRxivPreprintJan 18, 2024

The N-terminus of Plasmodium falciparum Circumsporozoite Protein Contains Three Non-Overlapping Murine B-cell Epitope Regions

Nathan Beutler, Elijah Garcia, Yen‐Chung Lai…·Thomas F. Rogers

This study identifies three non-overlapping B-cell epitope regions in the N-terminus of Plasmodium falciparum CSP using monoclonal antibodies from immunized mice.

1 citation

plant (other)proteomics

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