Sangwon F. Kim

This study shows that IPMK deficiency in skeletal muscle leads to metabolic disorders including weight gain, glucose intolerance, and reduced exercise capacity.

This study shows that time-restricted feeding reduces NASH symptoms in mice by increasing hepatic IPMK levels and decreasing inflammation.

This study shows that excess free fatty acids (FFA) reduce IPMK expression and Akt phosphorylation in mouse hepatocytes, contributing to insulin resistance and NAFLD.

This study shows that IPMK regulates hepatic insulin signaling and gluconeogenesis, with loss of IPMK leading to increased glucose production and insulin resistance in mice.