Author
The Francis Crick InstituteORCID 0000-0002-3918-2310Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Adrian Melo-Carrillo, Enrica Pellegrino, Parithi Balachandran…·William C. Skarnes
Chak Hon Luk, Gabriel L. Conway, Kim Jee Goh…·Maximiliano Gabriel Gutierrez
A single-donor iPSC-derived alveolar chip with epithelial, endothelial and macrophage cells models early Mycobacterium tuberculosis infection and shows ATG14-deficient macrophages die more without extra bacterial replication.
Stefano De Tito, Eugènia Almacellas, Daniel Dai Yu…·Sharon A. Tooze
The paper shows ATG9A and ARFIP2 work together to regulate PI4P levels for lysosomal repair during damage and bacterial infection.
Kyle W. Wettschurack, William C. Skarnes, Enrica Pellegrino…·Yang Yang
The paper develops an all-RNA prime editing system achieving over 95% editing efficiency in human iPSCs with minimal off-target effects.
Rebecca Morrison, Simeon R. Mihaylov, Chak Hon Luk…·Maximiliano Gabriel Gutierrez
This study identifies LRRK2-G2019S-dependent lysosomal membrane repair defects in macrophages leading to increased cell death.
Claudia Dell’Amico, Marilyn M. Angulo Salavarria, Yutaka Takeo…·Marco Onorati
This study shows that WDR62 mutations disrupt Golgi-to-spindle pole shuttling in neural progenitors, leading to neurodevelopmental abnormalities in microcephaly.