Cell BiologybioRxivPreprint
LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death
Rebecca Morrison, Simeon R. Mihaylov, Chak Hon Luk…·Maximiliano Gabriel Gutierrez
This study identifies LRRK2-G2019S-dependent lysosomal membrane repair defects in macrophages leading to increased cell death.